Methodology

How TCI reviews published evidence

TCI is an experimental evidence-review tool that retrieves and organizes published literature associated with dietary-supplement ingredients.

Output

TCI generates calibrated and accurate source-linked dossiers automatically.

Automated checks

The software includes automated checks that cited PubMed records resolve and that quoted snippets match retrieved source text.

Process

How an audit runs.

When a stage does not complete, the dossier shows that state instead of a result.
  1. 01

    Submit

    A partner submits a product and the label claims to review.

  2. 02

    Search

    TCI searches PubMed, OpenAlex and Europe PMC for the product's ingredients, and for the label claims whose outcomes it covers.

  3. 03

    Screen

    Retrieved records are screened for eligibility. Scanned, screened, eligible and analyzed counts are shown; an unrecorded count is marked unrecorded, never zero.

  4. 04

    Extract

    Findings are taken from the source text and written as assertions paired with their citations.

  5. 05

    Check

    The software includes automated checks that cited PubMed records resolve and that quoted snippets match retrieved source text.

  6. 06

    Record

    The dossier is stored as a versioned, append-only record, with its coverage gaps and failures intact.

Artifact contract

Built around sources and visible limits.

A dossier shows its evidence beside the sources, and shows what could not be assessed.

Assertion and citation pairs

Each conclusion is an assertion linked to the published records it cites.

Quoted source text

Where recorded, supporting, contrary, no-effect and context excerpts are quoted beside the citation, with a link to the record.

Search record

Where recorded, the dossier lists the searches it ran: provider, query and date. A missing search record is shown as a coverage gap.

Coverage gaps

Where TCI lacks the reference data, the dimension is marked not assessed. It is never averaged away.

Hazard states

Safety is reported as explicit hazard states, never as a single number.

Failures

A stage that did not complete stays visible with its state. It is never shown as no evidence, complete or safe.

Result states

Every check ends in an explicit state.

An unanswered question never becomes a number. A missing result is shown as missing.

Evidence dimensions · 5 states

  • Measured finding

    MEASURED_FINDING

    The required check ran and recorded eligible evidence.

  • Completed search — no eligible evidence identified

    NO_ELIGIBLE_EVIDENCE_IDENTIFIED_AFTER_COMPLETED_SEARCH

    The search completed and identified no eligible evidence. This is not a weak positive.

  • Not applicable

    NOT_APPLICABLE

    This check does not apply to this subject.

  • Not assessed — coverage gap

    NOT_ASSESSED_COVERAGE_GAP

    TCI lacks the required reference or execution record here. No conclusion was made.

  • Processing failure — retry required

    PROCESSING_FAILURE_RETRY_REQUIRED

    The check did not complete. This is not no evidence, complete, or safe.

Safety · 4 hazard states

  • Hazard identified — review required

    HAZARD_IDENTIFIED_REVIEW_REQUIRED

  • No listed hazard found in covered checks

    NO_LISTED_HAZARD_FOUND_IN_COVERED_CHECKS

  • Hazards not assessed

    NOT_ASSESSED

  • Hazard processing failure

    PROCESSING_FAILURE

A hazard state describes the cited evidence. It is not a safety determination.

Scope of the output

This output is an evidence-review aid. It does not determine that a supplement is safe, effective, legally compliant, or approved or endorsed by the FTC or FDA.