The clinical audit for supplement formulations.

Upload a label. Get a verification dossier backed by 8 AI agents, deterministic scoring, and peer-reviewed clinical evidence.1 Every score traced to specific PubMed studies.2

tci-cli
0+
Clinical Studies Analyzed
PubMed-Verified
PubMed-Verified Citations
FTC & FDA
FTC & FDA Compliance Built In
0
PubMed Studies Indexed
  • PubMed·
  • PMC·
  • Unpaywall·
  • Europe PMC·
  • OpenAlex·
  • FDA 21 CFR 101.93·
  • FTC Health Products Guidance·

Core Capabilities

The supplement industry runs on claims.
We run on evidence.

Existing certifications test whether the bottle matches the label. We test whether the formulation works — dose by dose, study by study.

Clinical Scoring Engine

Every ingredient scored against real clinical trials. Dose adequacy, evidence quality, bioavailability — each traced to specific PubMed studies.

EV
87
DA
73
BA
82
CompositeSCS: 76.1 · B
Learn more →

Regulatory Intelligence

Built-in FTC and FDA compliance checking. Flag disease claims, weak substantiation, and missing disclaimers before regulators do.

PASS"Promotes heart health"
FLAG"Prevents heart disease"
REWRITE"May support cardiovascular function"
Learn more →

R&D Simulation

Test your formulation before you manufacture. Get a predicted TCI score with optimization suggestions backed by real evidence.

SCS Prediction
Current62
Optimized78
+16 pts improvement
Learn more →
MULTI-AGENT ARCHITECTURE
TCI-PIPE-00

8 AI agents, 4 deterministic checks. One verified dossier.

From Opus-vision label intake through concurrent PubMed retrieval to 100% deterministic scoring — every score is traceable to a verified PMID.

20+ studies analyzed per ingredientClinical-grade sourcing in minutes, not weeks
INTAKEPARALLEL ANALYSISSYNTHESISVERIFIED OUTPUT
STUDIES SCANNED
847
CITATIONS VERIFIED
250/250
AGENTS
8 LLM · 4 DET
ANALYSIS TIME
14.0s
IntakeOPUS10 ingredientsClassifyDETroles setEvidenceHAIKU847 studiesVerifierDET250/250 ✓FormulationHAIKUDA 73 · BA 82DustingDET1 flaggedClaimsHAIKUFTC passSafetyHAIKUsafeCOAHAIKUverifiedScoringDETSCS 76.1SynthesisSONNETdossierQA ReviewHAIKU97% qualityVERIFIEDGrade BSYNTHESIS ENGINELLM agentDeterministicSonnet (synthesis)Four-tier badge
Cited Evidence250 citations verified
RCTPMID:38749210n=214
SRPMID:37421855n=1847
MAPMID:36190322n=3201
RCTPMID:35512236n=66
RCTPMID:34820119n=128
RCTPMID:33845612n=89
RCTPMID:33181086n=40
RCTPMID:30630782n=63
MechPMID:30275567
RCTPMID:29599478n=120
RCTPMID:27853523n=60
PKPMID:23072529n=24
RCTPMID:38749210n=214
SRPMID:37421855n=1847
MAPMID:36190322n=3201
RCTPMID:35512236n=66
RCTPMID:34820119n=128
RCTPMID:33845612n=89
RCTPMID:33181086n=40
RCTPMID:30630782n=63
MechPMID:30275567
RCTPMID:29599478n=120
RCTPMID:27853523n=60
PKPMID:23072529n=24
Pipeline Log
[intake] Opus-4.7 vision · 10 ingredients parsed · units normalized
[classify] roles assigned · PRIMARY ×4 · SUPPORTING ×6 (deterministic)
[evidence] PubMed "ashwagandha" AND "cortisol" AND "randomized" → 127 hits
[verifier] PMID:34820119 · snippet provenance OK · 250/250 verified
[formula] ashwagandha 300mg vs 300-600mg clinical range → ADEQUATE
[dusting] 1 ingredient below sub-clinical threshold → flagged (free)
[claims] FTC net-impression scan · 21 CFR 101.93 → PASS
[scoring] deterministic composite · SCS 76.1 · Grade B (no LLM math)
[synth] Sonnet-4.6 narrative · pathway coverage 92% · 3 synergies
[qa-gate] score-narrative consistency: PASS · citation integrity: PASS
[output] ✓ Grade B · CLINICALLY VERIFIED · dossier live

Follow one audit

One label in. One verified dossier out.

Scroll to watch a single formulation travel the same pipeline shown above — every stage real, every score traceable to a PMID.

01 · Intake

A label becomes structured data.

Opus-vision reads the Supplement Facts panel the way a chemist would — every ingredient, dose, and unit normalized, roles assigned deterministically.

  • 10 ingredients parsed
  • Units normalized to mg/IU
  • PRIMARY vs SUPPORTING roles
intake · opus-4.7 vision
Supplement Facts
Serving Size 2 Capsules · 30 Servings
CoQ10200mg
Ashwagandha50mg
Magnesium250mg
PQQ20mg
Vitamin D32000IU
Longevity Formula Pro · Lot 2026-114
label image
Parsed · units normalized10 ingredients
CoQ10 (ubiquinone)200 mgPRIMARY
Ashwagandha (root extract)50 mgPRIMARY
Magnesium (glycinate)250 mgPRIMARY
PQQ (pyrroloquinoline quinone)20 mgSUPPORTING
Vitamin D3 (cholecalciferol)2000 IUSUPPORTING
+ 5 more · roles assigned deterministically
02 · Evidence

Every ingredient meets the literature.

Each ingredient fans out to PubMed with clinical search grammar. Every returned study is provenance-checked — fabricated or unverifiable PMIDs never survive.

  • 847 studies scanned
  • 253 citations verified
  • 0 fabricated PMIDs kept
evidence · pubmed retrieval + verifier
[pubmed] "coq10" AND "mitochondrial" AND "randomized" 214 hits
[pubmed] "ashwagandha" AND "cortisol" AND "randomized" 127 hits
[pubmed] "magnesium glycinate" AND "sleep quality" 96 hits
[verifier] snippet provenance · fuzzy-match ≥ threshold · fabricated PMIDs rejected
RCTPMID:38749210n=88RCTPMID:41023891n=125METAPMID:36877404k=13RCTPMID:39284756n=46RCTPMID:34820119n=128METAPMID:41199218k=17+247 more
STUDIES SCANNED
847
CITATIONS VERIFIED
253
FABRICATED / REJECTED
0 kept
03 · Scoring

The math is Python, not opinion.

Sub-scores weight into a composite in fixed, auditable code. LLMs write narrative; they never touch a number. Flags that move the score are shown, not buried.

  • 100% deterministic scoring
  • Dusting + synergy flags
  • SCS 76.1 · Grade B
scoring · deterministic python — no LLM math
EVEvidence
87× 35%
DADose adequacy
73× 30%
BABioavailability
82× 20%
SFSafety
95× 15%
Ashwagandha dusted — 50mg vs 300–600mg clinical range
Synergy detected — PQQ + CoQ10, mitochondrial biogenesis
Composite · fixed weights · renormalized
SCS 76.1 · B
04 · Dossier

One verifiable dossier.

Everything composes into a defensible evidence package — executive summary, per-ingredient analysis, full citation list, and an embeddable trust badge.

  • 30+ page PDF + Excel workbook
  • Public dossier URL
  • Embeddable badge
theclinicalindex.com/dossier/a7f3e901
Longevity Formula Pro✓ VERIFIED
TCI-2026-A7F3E901 · 253 citations · 12 agents
76B
Executive summary

Strong evidence backing for 8 of 10 ingredients — CoQ10 and Vitamin D3 show the highest clinical support. Ashwagandha flagged at 50mg (8–16% of the validated range). One synergy detected: PQQ + CoQ10…

38749210CoQ10 supplementation improves mitochondrial…
94%
41023891Ashwagandha root extract reduces cortisol…
91%
30+ page PDFExcel workbookEmbeddable badgePublic dossier URL

Products

Four tools. One evidence engine.

From compliance auditing to formulation R&D to full verification to marketing claims — each powered by the same clinical scoring pipeline.

AUDIT
TCI-AUDIT-01
1.0
AUDIT

Find out what's wrong before the FTC does.

Paste any product URL. TCI scrapes every health claim, classifies risk by FTC/FDA standard, and generates copy-paste compliant alternatives.

3 claims flagged · 2 rewrites · FTC/FDA checked
theclinicalindex.com/audit
Audit Results
Best Creatine 2026 · Amazon
60
RISK
3
FAIL
15
MODIFY
18
SAFE
#1FAILHIGHdisease claim · T3 · bullet

“Clinically shown to support healthy testosterone by modulating the hypothalamic-pituitary-gonadal axis.”

FDA ANALYSIS

Naming COX-2 as a target is mechanistically specific and borders on disease language. COX-2 inhibitors are arthritis drugs.

FTC ANALYSIS

Requires Level 2 substantiation. Naming specific pathways elevates this to a specific functional claim.

123
EVIDENCE (10 STUDIES)
35311615375136763648096938409646349599923531541829018060364794813672071136231195
RCTs: 1Meta: 7
REPLACEMENT

“Supports the body's natural inflammatory response through antioxidant activity.”

§ 21 CFR 101.93(g)(2)(iv)(C), (v); FDA Structure/Function Guidance (2016); FTC 2022 Guidance II.B
#4MODIFYstructure/function

“Creatine supports cognitive processing speed, working memory, and mental endurance.”

Hover to play
FORMULATE
TCI-FORM-02
2.0
FORMULATE

Predict your score before you manufacture.

Input your ingredients, doses, and target claims. Get a predicted TCI score with optimization suggestions — each backed by specific PMIDs.

SCS: 72 → 84 · 3 dose optimizations · 2 interaction flags
theclinicalindex.com/formulate
SIMULATION RESULTS
75
B
Evidence87
Dose Adequacy68
Bioavailability80
INGREDIENTS
Methylfolate10mg
90HIGH
Lithium Orotate10mg
86ADEQUATE
Magnesium250mg
58LOW
OPTIMIZATIONup to +39 pts
Applied — Magnesium increased to 1429mg
DOSEhigh confidence
+5PTS
Add Vitamin B6 (Mg cofactor)
ADDmedium
+5PTS
Add Vitamin D (Mg cofactor)
ADDmedium
Hover to play
VERIFY
TCI-VRFY-03
3.0
VERIFY

Get the full clinical evidence dossier.

Submit your product for deep verification. 8 AI agents and 4 deterministic checks analyze every ingredient against PubMed and produce a defensible evidence report with embeddable trust badge.

847 studies · 250 citations verified · 8 AI + 4 det · 47.3s
theclinicalindex.com/verify
59fdf972-a1cd-45ef✓ VERIFIED
Shilajit Matrix
Analyzed March 5, 2026
80B+
Score Breakdown
Evidence35%
73
Dose30%
75
Bioavail.20%
98
Safety15%
76
Executive Summary

Shilajit Matrix® combines six primary ingredients targeting NAD+ metabolism and mitochondrial function. The 500mg shilajit and 200mg CoQ10 meet clinical thresholds, while urolithin A at 250mg falls below the 500mg standard. Strong bioavailability optimization with comprehensive safety profile.

Ingredient Analysis
Purified Shilajit Extract500mgPRIMARY
EV 88DA 79BA 84
83.5

Moderate clinical evidence for mitochondrial support. Three RCTs show improvements at 250-500mg/day. PMID 35933897 demonstrates dose-dependent bone preservation over 48 weeks.

Ubiquinol (CoQ10)200mgPRIMARY
EV 75DA 90BA 95
85
PQQ (BioPQQ®)20mgPRIMARY
EV 85DA 80BA 80
81.5
Urolithin A250mgPRIMARY
EV 80DA 35BA 70
62.4
Verification
PMIDs103/103
Snippets103/129
HallucinationPASSED
Duration3m 47s
Validity
EXPIRES
March 5, 2027
Actions
VERIFIED
Hover to play
MARKET
TCI-MRKT-04
4.0
MARKETCOMING SOON

Generate claims you can actually make.

Turn your evidence into platform-specific marketing copy. Amazon-safe. Shopify-ready. Ad-compliant.

4 platforms · 12 compliant claims · confidence 87%
theclinicalindex.com/claims
Shilajit Matrix — Claims
Amazon · Shopify · Ads
4 claims · 2 blocked
AmazonShopifyAds
Energy
92
SAFE

Supports cellular energy production with clinically studied CoQ10 at 200mg — the dose used in human trials for mitochondrial function.

Vitality
87
SAFE

Contains PrimaVie® Shilajit Extract standardized to >50% fulvic acid, shown in 3 RCTs to support healthy testosterone levels in men.

Cognitive
78
CAUTION

BioPQQ® at 20mg supports cognitive function including memory and attention based on 6 randomized controlled trials.

Add disclaimer: individual results may vary
General
95
SAFE

Premium mitochondrial support formula featuring 11 synergistic ingredients with third-party verified dosing.

NOT ALLOWED (2)

Clinically proven to reverse aging at the cellular level

Disease claim — implies treatment

Cures fatigue and brain fog

Unapproved drug claim language
Hover to play

AI Detection

What the AI catches that humans miss.

Dusting Detector

Catches "fairy dusting" — ingredients at sub-clinical doses included for label decoration.

Ashwagandha50mg
Clinical dose: 300–600mg
Ratio: 8–16% of clinical dose
DUSTED
ref: PMID:34820119 · RCT · n=128
FTC/FDA Compliance
PASS

"Promotes heart health"

FAIL

"Cures heart disease"

SUGGESTED

"May support cardiovascular function"

ref: 21 CFR 101.93 · FTC Health Products Guidance 2023
Bioavailability Analysis
Magnesium Oxide4%

Source: PMID:23072529 · n=46

Mag Glycinate80%

Source: PMID:34901522 · n=48

+18 points by switching forms
Synergy & Interaction Map
PQQ + CoQ10
Mitochondrial biogenesis synergy
ALA + NR
Separate by 2hrs for optimal absorption
Astaxanthin
Needs lipids for absorption
4 interactions detected →

The Deliverable

Every claim traced. Every score verified.

Upload a label, get a 30+ page clinical evidence dossier — ready for compliance, retail buyers, or your own R&D team.

[CI]
Clinical Verification Dossier
Longevity Formula Pro
Score 76.1
Grade B
Citations 250
Agents 12
Executive Summary

This formula demonstrates strong evidence backing for 8 of 10 ingredients, with CoQ10 and Vitamin D3 showing the highest clinical support. Ashwagandha is flagged at 50mg — 8-16% of the clinically validated dose range (300-600mg). One synergy detected: PQQ + CoQ10 for mitochondrial biogenesis...

Top Evidence
38749210CoQ10 supplementation improves mitochondrial...
94%
41023891Ashwagandha root extract reduces cortisol...
91%
39284756Magnesium glycinate and sleep quality in...
88%
Score Breakdown
EV87
DA73
BA82
SF95
Generated: 2026-03-06ID: TCI-2026-A7F3E901
Executive Summary
Key findings, formula strengths, and flagged concerns in plain language.
Evidence Table
Every citation linked to PubMed with extraction confidence scores.
Dose & Bioavailability
Clinical dose ranges vs actual doses, form analysis, absorption ratings.
Safety Assessment
UL violations, drug interactions, population-specific contraindications.
Claims Verdicts
Each marketing claim rated supported, overreach, or unsupported.
Audit Trail + Workbook
Full methodology appendix plus Excel workbook with raw evidence data.
100% Verifiable — Every PMID links to PubMed. Every snippet is traceable.
TRUST BADGE
TCI-BDGE-05

Turn verification into conversion.

Embed your Clinical Index score directly on your product page. Give shoppers the clinical proof they need to click buy.

+23%add-to-cart rate

Products displaying third-party verification badges see significantly higher conversion rates. Shoppers trust clinical evidence over marketing claims.

Expandable trust widget
Score, ingredient breakdown, and evidence links — all without leaving the product page.
Works everywhere
One embed code. Shopify, Amazon storefronts, custom sites. Drop it in and it works.
Always current
Badge updates automatically when you re-verify. No manual maintenance.
WITHOUT
WITH BADGE
Stellar Health Labs
Creatine Monohydrate — Clinical Grade
100% Pure Micronized · 50 Servings
$28.82$33.90SAVE 15%
ADD TO CART
Buy with shop
🛡 90-Day Guarantee🚚 Free Shipping
Clean, single-ingredient formula
Pharmaceutical-grade purity
Optimized clinical dosing
Third-party tested
Lab & evidence verified byClinical IndexCOA
95/100
95A+

This formula is well-supported by clinical evidence at the doses listed.

20 studies·Verified Feb 2026·Lab tested
PRIMARY INGREDIENTS
Creatine Monohydrate5000mg
Clinically dosed
Ingredient DosesEvidence QualityBioavailabilityPurity
THECLINICALINDEX.COM
View Full Dossier
Stellar Health Labs
Creatine Monohydrate — Clinical Grade
100% Pure Micronized · 50 Servings
$28.82$33.90SAVE 15%
ADD TO CART
Buy with shop
🛡 90-Day Guarantee🚚 Free Shipping
Clean, single-ingredient formula
Pharmaceutical-grade purity
Optimized clinical dosing
Third-party tested
Drag to compare

Pricing

One price per audit. No subscriptions.

Every audit is the full analysis — no feature gating. Buy credits when you need them; they never expire.

Your first audit is free — no credit card required

Single Audit

$49

1 audit credit

Buy 1 Audit
  • Full ingredient analysis
  • 15+ studies per ingredient
  • PDF dossier + Excel workbook
  • FTC compliance check
Best Value

10-Pack

$399

$39.90 per audit · save 19%

Buy 10 Audits
  • Everything in Single Audit
  • Credits never expire
  • Verification badge + embed
  • Permanent web dossier access
  • Priority support

30-Pack

$799

$26.63 per audit · save 46%

Buy 30 Audits
  • Everything in 10-Pack
  • For growing catalogs
  • Bulk re-verification
  • Enterprise options available

Need API access, white-label PDFs, or bulk pricing? Talk to us · See everything included

Ready to know what the evidence actually says about your product?

Free to start. No credit card required.

Citations on this page
1.
PMID:36877404META-ANALYSISEffects of Creatine Monohydrate on Endurance Performance in a Trained Populationk=13 · 2023
2.
PMID:38749210RCTCoQ10 supplementation improves mitochondrial function — randomized controlled trialn=88 · extraction confidence 94%

Sample-dossier citations shown for illustration. In a live dossier, every citation links to PubMed and carries a verbatim, provenance-checked snippet — see the full citation list in the sample dossier